If the scope aligned itself to start with, it should go to an object you choose. Then, if you move with the arrow keys, the scope should continue to track the new spot that is in the center. If the scope is tracking just fine and then stops when you use the arrow keys, then something is wrong.
It could be that the gear training is off a bit, leaving some slack in the gears when you make a move in a particular direction. There is a routine for that in the menu called, "Drive Training" or something similar. I think it is in the "Setup" menu, but it could be under utilities. For the LS, you do this at night when the stars are out. The scope will do the whole procedure itself using the camera, using a bright star. If training the drives does not take care of the problem, call Meade Customer Support, tell them what you have done so far to remedy the problem, and see if they have any recommendations.
There is a routine in the menu for putting objects in the center, but I do not remember, off the top of my head, what it is called. It basically sets the arrangement between the scope and its camera, which can get off a bit. Mine got bumped one time when I was traveling and moved the camera position a tiny bit. I used this function to re-center the object in the field. After that, everything was centered.
Hope this helps,